Science behind HiveAlive

Research topics

Effect on Chalkbrood

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Effect on Foulbrood

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Effect on Hive Production

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Effect on Colony Population

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Effect on Nosema

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Effect in Cage Trials

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French trial stats



Feeding HiveAlive resulted in

  • Increased Honey/Pollen Production
  • Increased Brood Production
  • Increased Colony Population (similar results seen in trials carried out in Greece)




3 Graph French trial honey Nov2016




The amount of honey and pollen stored by hives was also monitored by counting the number of frames of stores per hive. At the end of the trial, the HiveAlive group had 40% more stores than the control group.




2 Graph French trial brood nov2016





The amount of brood on frames was measured in terms of area coverage (m2) of frames per hive. At the end of the trial period, the HiveAlive group had 35% more brood than the control group.



Increased Honey Production Supplement



The number of spaces between frames that was full of bees was noted as a method of assessing colony population. The HiveAlive group had more bees than the control group at the end of the trial period. Feeding HiveAlive resulted in a 20% increase in colony population compared to control.  





The ability of colonies to draw out new wax comb was monitored for the first summer period after feeding began. Just 3 weeks after feeding, the HiveAlive group were drawing out 7% more comb than the control group.


Read the full paper  


Greek trial stats


  • Published in the Journal of Apicultural Research - Trials were performed by the Hellenic Institute of Apiculture, Greece. Read the published paper.
  • Increased Population - A near doubling (89%) in colony population in comparison to ordinary syrup when used biannually. Similar results seen in French trial.
  • Lower Nosema Levels - HiveAlive treatment group maintained significantly lower levels of Nosema ceranae spores.
  • Lower Winter Mortality - None of the 20 colonies fed syrup with HiveAlive™ failed whilst 3 hives failed in the syrup only group. 




Overwinter Bee Protection Supplement




Feeding of colonies with HiveAlive results in a large increase in colony population compared to control with continued use. Colonies are significantly stronger after one year of feeding but best results are observed with continued annual usage. Feeding HiveAlive for a year and a half resulted in an 89% increase in colony population compared to control.





Overwinter Bee Protection Supplement




It was also found that feeding HiveAlive maintains low levels of Nosema spores.

Levels of Nosema naturally reduce in summer months and increase over winter. Feeding HiveAlive kept the Nosema levels lower than control over winter and in spring. 




Overwinter Bee Protection Supplement




The HiveAlive fed group had reduced overwinter mortality compared to the control group. The control group experienced 15% losses whilst the HiveAlive group had no losses.







Read the peer-reviewed journal article  


Read the full paper  


Overwinter Bee Protection Supplement



A number of feeding methods were compared in order to find out which had the greatest effect on Nosema spore levels.

Feeding HiveAlive overwinter resulted in a 92% decrease in the number of spores compared to control.

Results also suggest that adding HiveAlive to syrup is the most effective. 





Read the full paper  


HiveAlive inhibits ChalkbroodChalkbrood is one of the most common and widely recognised fungal diseases that affects honeybee brood, the causative agent of which is Ascosphaera apis. Currently, there are no approved treatments for the management of Chalkbrood infection. Anecdotal evidence from beekeepers suggests that use of HiveAlive may cause a reduction in Chalkbrood infection.

A number of in-vitro tests were carried out to assess this hypothesis including agar dilution assays and 96 well plate microdilution assays. A concentration of 0.25% inhibited the growth and sporulation of A. apis on agar plates. Results from the 96 well microdilution assays suggest that even lower concentrations may be effective at inhibiting growth. Further research is required to examine effects in a hive setting.


Read the full paper  



HiveAlive inhibits American Foulbrood (AFB)American Foulbrood (AFB) is caused by a bacterium called Paenibacillus larvae. Oxytetracycline is used to treat infections but strains of oxytetracycline resistant P. larvae have been identified in some countries. 

Different concentrations of HiveAlive were evaluated for their inhibitory potential using agar-dilution assays and 96-well microdilution assays. A concentration of 0.25% HiveAlive in agar was sufficient at inhibiting growth on solid media. In liquid media, growth appeared to be inhibited at 0.625%. Further tests are required to define the minimum inhibitory concentration and to assess if this inhibitory action can be replicated in larvae.


Read the full paper  



hivealive reduces nosema






Results generated from short term cage trials demonstrate the following:

  • HiveAlive reduces Nosema ceranae Spores by 56% in 7 days
  • Addition of seaweed extracts to thymol improves spore reduction by 91%
  • Bees prefer syrup with HiveAlive added



HiveAlive Italy trial nosema






The effects of adding seaweed extracts were assessed by testing a blend with seaweed extract and without seaweed extracts. 

It was found that addition of the seaweed extracts reduced Nosema spores much more effectively than the blend without the seaweed extracts. 




Read the full paper  


What beekeepers think about HiveAlive

Key Active Ingredients


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HiveAlive is largely composed of a unique blend of scientifically selected Irish seaweed extracts called OceaShield which has many beneficial properties. Seaweeds are routinely fed in animal feeds to help reduce the need for antibiotics.

HiveAlive contains thyme which is recognised as a key substance in the fight against Nosema. We have developed a unique emulsification process to ensure it blends easily into sugar syrup and does not cause separation or re-crystallisation.

HiveAlive contains a precise amount of lemongrass in order to increase attractiveness of syrup but does not contain enough to induce unwanted robbing. Lemongrass also has a calming effect on bees.

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HiveAlive is an Advance Science brand


HiveAlive is an Advance Science brand

About Us

At Advance Science, we are heavily research focused and strive to provide natural, effective and practical solutions that are cost competitive for the beekeeper. Our research is centred on utilising and validating nature’s best defences followed by expert formulation and blending. We ensure that these processes are sustainable and work in harmony with nature.


Customer Service

Advance Science Ltd.,
Business Innovation Centre.
National University of Ireland,

R&D Hub

Forbairt Eolaíochta Teo,
Loch Eidhneach,
Sraith Salach,
Co. na Gaillimhe,

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